RGD peptide (GRGDNP) (TFA)

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RGD peptide (GRGDNP) (TFA)  纯度: 99.25%

RGD peptide (GRGDNP) (TFA)作为整合素-配体相互作用的抑制剂,在细胞黏附、迁移、生长和分化中发挥重要作用。RGD peptide (GRGDNP) (TFA)通过激活构象变化促进细胞凋亡,从而增强caspase-3的活化。

RGD peptide (GRGDNP) (TFA)

RGD peptide (GRGDNP) (TFA) Chemical Structure

规格 价格 是否有货 数量
1 mg ¥600 In-stock
5 mg ¥1200 In-stock
10 mg   询价  
50 mg   询价  

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RGD peptide (GRGDNP) (TFA) 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

RGD peptide (GRGDNP) (TFA) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].

分子量

728.63

Formula

C25H39F3N10O12

Sequence

Gly-Arg-Gly-Asp-Asn-Pro

Sequence Shortening

GRGDNP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : ≥ 50 mg/mL (68.62 mM)

DMSO : ≥ 50 mg/mL (68.62 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3724 mL 6.8622 mL 13.7244 mL
5 mM 0.2745 mL 1.3724 mL 2.7449 mL
10 mM 0.1372 mL 0.6862 mL 1.3724 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).

    [2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50.

    [3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

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