N-Boc-piperazine

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N-Boc-piperazine  纯度: 99.96%

N-Boc-piperazine 是一种 PROTAC linker，属于 Alkyl/ether 类。可用于合成 PROTAC PD-1/PD-L1 degrader-1 (HY-131183)。

N-Boc-piperazine

N-Boc-piperazine Chemical Structure

CAS No. : 57260-71-6

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
500 mg ￥350 In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

N-Boc-piperazine 相关产品

•相关化合物库:

  • Fragment Library

生物活性

N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

186.25

Formula

C9H18N2O2
CAS 号

57260-71-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务