Levoleucovorin Calcium(Synonyms: Calcium levofolinate; CL307782)

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Levoleucovorin Calcium (Synonyms: Calcium levofolinate; CL307782) 纯度: 99.50%

Levoleucovorin Calcium 是folinic acid的活性形式。

Levoleucovorin Calcium(Synonyms: Calcium levofolinate; CL307782)

Levoleucovorin Calcium Chemical Structure

CAS No. : 80433-71-2

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in Water ￥1045 In-stock
100 mg ￥950 In-stock
500 mg ￥2100 In-stock
1 g ￥3100 In-stock
2 g ￥4100 In-stock
5 g   询价  
10 g   询价  

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生物活性

Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid. IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself.

Clinical Trial

分子量

511.50

Formula

C20H21CaN7O7
CAS 号

80433-71-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶解性数据
In Vitro: 

H2O : 10 mg/mL (19.55 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9550 mL 9.7752 mL 19.5503 mL
5 mM 0.3910 mL 1.9550 mL 3.9101 mL
10 mM 0.1955 mL 0.9775 mL 1.9550 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Levomefolic acid. From Wikipedia, the free encyclopedia

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