L-Azidohomoalanine hydrochloride

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L-Azidohomoalanine hydrochloride  纯度: 99.76%

L-Azidohomoalanine hydrochloride 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

L-Azidohomoalanine hydrochloride

L-Azidohomoalanine hydrochloride Chemical Structure

CAS No. : 942518-29-8

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥1210 In-stock
50 mg ￥1100 In-stock
100 mg ￥1800 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

180.59

Formula

C4H9ClN4O2
CAS 号

942518-29-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 125 mg/mL (692.18 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.5374 mL 27.6870 mL 55.3741 mL
5 mM 1.1075 mL 5.5374 mL 11.0748 mL
10 mM 0.5537 mL 2.7687 mL 5.5374 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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