2-Keto Crizotinib(Synonyms: PF-06260182)

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2-Keto Crizotinib (Synonyms: PF-06260182)

2-Keto Crizotinib (PF-06260182) 是有活性的克唑替尼的内酰胺代谢产物。

2-Keto Crizotinib(Synonyms: PF-06260182)

2-Keto Crizotinib Chemical Structure

CAS No. : 1415558-82-5

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

2-Keto Crizotinib (PF-06260182) is an active lactam metabolite of crizotinib.

体外研究
(In Vitro)

2-Keto Crizotinib (PF-06260182) is active and considerably less potent than crizotinib, and it is not thought to contribute significantly to the in vivo activity of crizotinib.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

464.32

Formula

C21H20Cl2FN5O2
CAS 号

1415558-82-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Balis FM, e al. First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot Consortium. Cancer Chemother Pharmacol. 2017 Jan;79(1):181-187.

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