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AcLysValCit-PABC-DMAE-SW-163D
AcLysValCit-PABC-DMAE-SW-163D 是抗体偶联药物的一部分 (drug-linker conjugates for ADC), 由天然的双嵌入剂SW-163D 和 linker AcLysValCitPABC-DMAE 偶联构成。
AcLysValCit-PABC-DMAE-SW-163D Chemical Structure
CAS No. : 2411007-69-5
| 规格 | 是否有货 | ||
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker[1]. |
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| 体外研究 (In Vitro) |
SW-163D is a cyclodepsipeptide antibiotic that is isolated from Streptomyces sp. SW-163D also exhibits antitumour activity. PF06888667 is a potent, stable, and efficacious ADC that consists of the bis-intercalator, SW-163D, conjugated via an N-acetyl-lysine-valine-citrulline-p-aminobenzyl alcohol-N,N-dimethylethylenediamine (AcLysValCitPABC-DMAE) linker to an engineered variant of the anti-Her2 mAb, trastuzumab, catalyzed by transglutaminase[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1817.05 |
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| Formula |
C85H113N19O22S2 |
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| CAS 号 |
2411007-69-5 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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