ERK2 IN-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ERK2 IN-1 

ERK2 IN-1 是一种选择性 ERK2 抑制剂,IC50 为 7 nM。

ERK2 IN-1

ERK2 IN-1 Chemical Structure

CAS No. : 1093061-47-2

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生物活性

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].

IC50 & Target[1]

ERK2

7 nM (IC50)

体外研究
(In Vitro)

ERK1/2 IN-1 (Compound 28) maintains good ERK enzymatic activity (ERK IC50=7 nM) and cellular activity in BRAF/KRAS mutant wildtype cancer cell lines (HT-29/Caspase IC50=118/80 nM)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

647.76

Formula

C36H34FN7O2S

CAS 号

1093061-47-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Boga SB, Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034.

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