UAMC-3203

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

UAMC-3203 

UAMC-3203是有效，选择性的 Ferroptosis 抑制剂，IC50为12 nM。

UAMC-3203

UAMC-3203 Chemical Structure

CAS No. : 2271358-64-4

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UAMC-3203 的其他形式现货产品:

UAMC-3203 hydrochloride

生物活性

UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.

IC50 & Target

IC50: 12 nM (Ferroptosis)[1]
体内研究
(In Vivo)

No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild type mice derived from a Gpx4 fl/fl breeding[1]
Dosage: 20 µmol/kg
Administration: Injected intraperitoneally; daily, over a period of 4 weeks
Result: No toxicity was observed.

分子量

471.66

Formula

C25H37N5O2S
CAS 号

2271358-64-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.

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