27-Methyl withaferin A

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27-Methyl withaferin A 

27-Methyl withaferin A (comppund 26) 是一种具有抗癌作用的凋亡 (apoptosis) 诱导剂。27-Methyl withaferin A 对 HeLa、A-549 和 MCF-7 人类肿瘤细胞系具有抗增殖作用，IC50 值分别为 3.2 μM、4.2 μM 和 1.4 μM。

27-Methyl withaferin A

27-Methyl withaferin A Chemical Structure

CAS No. : 1777780-93-4

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生物活性

27-Methyl withaferin A (comppund 26) is an apoptosis inducer with anticancer effects. 27-Methyl withaferin A shows antiproliferative effects against HeLa, A-549 and MCF-7 human tumor cell lines with IC50 values of 3.2 μM, 4.2 μM and 1.4 μM, respectively[1].

分子量

484.62

Formula

C29H40O6
CAS 号

1777780-93-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gabriel G Llanos, et al. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers. Eur J Med Chem. 2017 Nov 10;140:52-64.

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