TCO-OH

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TCO-OH 

TCO-OH 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

TCO-OH

TCO-OH Chemical Structure

CAS No. : 85081-69-2

规格 价格 是否有货
50 mg ￥5600 询问价格 & 货期
100 mg ￥9000 询问价格 & 货期

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生物活性

TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

126.20

Formula

C8H14O
CAS 号

85081-69-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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