上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Pifithrin-β (Synonyms: PFT β; Cyclic Pifithrin-α)
Pifithrin-β (PFT β) 是有效地 p53 抑制剂,IC50 值为 23 μM。
![Pifithrin-β Chemical Structure Pifithrin-β(Synonyms: PFT β; Cyclic Pifithrin-α)](http://www.fluoroprobe.com/wp-content/uploads/2022/05/hy-16702.gif)
Pifithrin-β Chemical Structure
CAS No. : 60477-34-1
规格 | 是否有货 | ||
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100 mg | 询价 | ||
250 mg | 询价 | ||
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Pifithrin-β 的其他形式现货产品:
生物活性 |
Pifithrin-β (PFT β) is a potent p53 inhibitor with an IC50 of 23 μM. |
IC50 & Target |
IC50: 23 μM (p53)[1] |
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体外研究 (In Vitro) |
Pifithrin-α, an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α is very unstable in culture medium and rapidly converts to its condensation product pifithrin-β (PFT β), the N-acetyl derivative[2]. After 24 h, the viability assay shows that the pretreatments with 1 and 10 μM pifithrin-β exerts neuroprotective effects[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
268.38 |
Formula |
C16H16N2S |
CAS 号 |
60477-34-1 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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