上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
SNIPER(TACC3)-11
SNIPER(TACC3)-11 是一种有效的成纤维细胞生长因子受体 3 转化酸性卷曲螺旋蛋白 3 (FGFR3-TACC3) 抑制剂。SNIPER(TACC3)-11 降低 FGFR3-TACC3 蛋白水平,抑制 FGFR3-TACC3 阳性癌细胞的生长。
SNIPER(TACC3)-11 Chemical Structure
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生物活性 |
SNIPER(TACC3)-11 is a potent FGFR3-TACC3 degrader. SNIPER(TACC3)-11 reduces FGFR3-TACC3 protein levels and suppressed the growth of FGFR3-TACC3 positive cancer cells[1]. |
IC50 & Target |
FGFR3-TACC3[1] |
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体外研究 (In Vitro) |
SNIPER(TACC3)-11 (compound 5a) (0.3-3 μM; 6 hours) reduces FGFR3-TACC3 levels[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis
Cell Proliferation Assay
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分子量 |
995.26 |
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Formula |
C51H66N10O7S2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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