FGFR4-IN-7

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

FGFR4-IN-7

FGFR4-IN-7 (Compound C3) 是一种共价可逆的 FGFR4 抑制剂，IC₅₀ 值为 0.42 μM。 FGFR4-IN-7 通过阻断 FGFR4 信号通路诱导细胞凋亡 (apoptosis)。FGFR4-IN-7可用于肝癌 (HCC) 的研究。

FGFR4-IN-7 Chemical Structure

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生物活性	FGFR4-IN-7 (Compound C3) is a covalent reversible FGFR4 inhibitor with an IC₅₀ value of 0.42 μM. FGFR4-IN-7 induces apoptosis via the FGFR4 signaling pathway blockage. FGFR4-IN-7 can be used for the research of hepatocellular carcinoma (HCC)^[1].
分子量	526.41
Formula	C₂₆H₂₅Cl₂N₅O₃
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Wenwen Nie, et al. Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors. Bioorg Chem. 2022 Apr;121:105673.

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