Carbonic anhydrase inhibitor 8

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Carbonic anhydrase inhibitor 8 

Carbonic anhydrase inhibitor 8 (compound R-13) 是一种苄基衍生物，一种有效的人碳酸酐酶 (hCA) 抑制剂，对 hCA I、hCA II、hCA IV 的 Ki 值分别为 60.7 nM、320.7 nM、2298 nM。

Carbonic anhydrase inhibitor 8

Carbonic anhydrase inhibitor 8 Chemical Structure

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生物活性

Carbonic anhydrase inhibitor 8 (compound R-13), a benzyl-derivative, is a potent human carbonic anhydrase (hCA) inhibitor with Ki values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively[1].

分子量

403.50

Formula

C20H25N3O4S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Niccolò Chiaramonte, et al. 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity. Eur J Med Chem. 2022 Jan 15;228:114026.

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