Antitumor agent-42 (Compound 15h) is a bifunctional agent exhibiting both tubulin polymerized inhibition and NO-releasing activities, resulting in potent anti-angiogenesis, colony formation inhibition, cell cycle arrest and apoptosis induction effects^[1].

Antitumor agent-42 (Compound 15h) is a potent antitumor agent, which towards A2780, MDA-MB-231, HCT-116 and A549 cells with IC₅₀ values of 0.012, 0.015, 0.011 and 0.008 µM, respectively^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

In the nude mice xenograft model, antitumor agent-42 significantly inhibited the paclitaxel-resistant tumor growth with low toxicity^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

575.39

C₂₄H₁₉BrN₂O₈S

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Xin Huang, et al. Synthesis and biological evaluation of novel hybrids of phenylsulfonyl furoxan and phenstatin derivatives as potent anti-tumor agents. Eur J Med Chem. 2022 Feb 15; 230:114112.