EZH2-IN-8

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

EZH2-IN-8 

EZH2-IN-8 是一种有效的 EZH2 抑制剂。EZH2 过表达或 SET 区突变 (Y641F、Y641N、A687V、A677G 点突变) 均导致 H3K27me3 异常升高，促进多种肿瘤的生长发育，如乳腺癌、前列腺癌、白血病等。EZH2-IN-8 具有研究癌症疾病的潜力 (摘自专利 WO2021129629A1，化合物 265)。

EZH2-IN-8

EZH2-IN-8 Chemical Structure

CAS No. : 2659225-08-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

EZH2-IN-8 is a potent inhibitor of EZH2. EZH2 overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) all lead to abnormal elevation of H3K27me3 and promote the growth and development of many types of tumors, such as breast cancer, prostate cancer, leukemia, etc. EZH2-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021129629A1, compound 265)[1].

分子量

570.74

Formula

C31H40F2N4O2S
CAS 号

2659225-08-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li Yao, et al. Zeste enhancer homologue 2 inhibitor and its use. Patent WO2021129629A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务