4′-Bromo-resveratrol(Synonyms: 4′‐BR)

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4′-Bromo-resveratrol (Synonyms: 4′‐BR)

4′-Bromo-resveratrol 是一种有效的双重抑制剂 Sirtuin-1Sirtuin-3。4′-Bromo-resveratrol 通过线粒体代谢重编程抑制黑色素瘤细胞的生长。4′-Bromo-resveratrol 通过代谢重编程和影响细胞周期和细胞凋亡信号传导在黑色素瘤细胞中发挥抗增殖作用。

4

4′-Bromo-resveratrol Chemical Structure

CAS No. : 1224713-90-9

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生物活性

4′-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4′-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4′-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].

分子量

291.14

Formula

C14H11BrO2

CAS 号

1224713-90-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. George J, et al. 4′-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. Mol Carcinog. 2019;58(10):1876-1885.

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