Methyl jasmonate

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Methyl jasmonate 

Methyl jasmonate 是一种参与植物在逆境下防御的植物激素。Methyl jasmonate 能提高蓝莓叶提取物 (主要是花青素) 的抗氧化性能,降低AGS细胞的活力和迁移能力。具有抗癌活性。

Methyl jasmonate

Methyl jasmonate Chemical Structure

CAS No. : 1211-29-6

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生物活性

Methyl jasmonate is a phytohormone involved in plant defenses under stress conditions. Methyl jasmonate can improve antioxidant properties of blueberry leaf extracts (mainly anthocyanins), and decrease the viability and migration capacity of AGS cells. Anticarcinogenic activity[1].

体外研究
(In Vitro)

Methyl jasmonate-treated blueberry leaf extraction (10-3200 μg/mL; 1 hour) can decrease cell viability of AGS cells with increasing dose[1].
Methyl jasmonate-treated blueberry leaf extraction (10-3200 μg/mL) can significantly decrease the expression of p-P70S6K (AKT/mTOR pathway) and p-ERK1/2 (MAPK) proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay

Cell Line: Gastric cancer cells (line AGS)[1]
Concentration: 10, 25, 50, 100, 200, 400, 800, 1600 and 3200 μg/mL
Incubation Time: 1 hour
Result: Cell viability of AGS cells gradually decreased in response to increasing doses of blueberry leaf extract from MeJA treated plants.

Western Blot Analysis

Cell Line: AGS cells[1]
Concentration: 10, 50, 100, 200, 400, 800, 1600 and 3200 μg/mL
Incubation Time:
Result: Blueberry leaf extracts of MeJA-treated plants significantly decreased the expression of p-P70S6K (AKT/mTOR pathway) and p-ERK1/2 (MAPK) proteins.

分子量

224.30

Formula

C13H20O3

CAS 号

1211-29-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Ribera-Fonseca A, et al. The Anti-Proliferative and Anti-Invasive Effect of Leaf Extracts of Blueberry Plants Treated with Methyl Jasmonate on Human Gastric Cancer In Vitro Is Related to Their Antioxidant Properties. Antioxidants (Basel). 2020;9(1):45. Published 2020 Jan 4.

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