上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Immunoproteasome inhibitor 1
Immunoproteasome inhibitor 1 是一种有效的、可逆的、依时独立的免疫蛋白酶体 (immunoproteasome) 和蛋白酶体 (proteasome) 抑制剂 (β5c、β1i、β5i亚基的Kis分别为1.18、0.27、1.91 μM)。Immunoproteasome inhibitor 1 可用于治疗一些肿瘤性疾病。
Immunoproteasome inhibitor 1 Chemical Structure
CAS No. : 2755772-63-3
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Immunoproteasome inhibitor 1 is a potent, reversible, time-independent immunoproteasome and proteasome inhibitor (Kis of 1.18, 0.27, 1.91 μM in β5c, β1i, β5i submits, respectively). Immunoproteasome inhibitor 1 can be used for the treatment of certain neoplastic diseases[1]. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
Immunoproteasome inhibitor 1 (compound 9) (0-25 μM; 0-600 seconds; in Human 20S immunoproteasome and human 20S proteasome) has high binding affinity for the β1i subunit (0.27 µM) of immunoproteasome and proteasome, coupling with good inhibitory properties towards β5i and β5c subunits. And the results of against the β5i subunit shows that the inhibition is reversible, time-independent[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
358.43 |
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| Formula |
C20H26N2O4 |
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| CAS 号 |
2755772-63-3 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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