Anticancer agent 39

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Anticancer agent 39 

Anticancer agent 39 (compound B12) 是济源冬凌草素 A (JOA) 的荧光衍生物，可诱导线粒体膜电位 (MMP) 的崩溃，从而诱导细胞凋亡。Anticancer agent 39 抑制细胞克隆和迁移。Anticancer agent 39 具有抗 HGC-27 细胞增殖活性 IC50 值为 0.39 μM。

Anticancer agent 39

Anticancer agent 39 Chemical Structure

CAS No. : 2762426-00-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].

分子量

896.08

Formula

C50H65N5O10
CAS 号

2762426-00-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chen Zhou, et al. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A. Eur J Med Chem. 2022 Feb 5;229:114048.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务