Carbonic anhydrase inhibitor 9

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Carbonic anhydrase inhibitor 9 

Carbonic anhydrase inhibitor 9 是一种有效的碳酸酐酶 (CA) 抑制剂，对 hCA II 和 IX 的 Ki 分别为 56.4 和 56.9 nM。 具有抗增殖活性。

Carbonic anhydrase inhibitor 9

Carbonic anhydrase inhibitor 9 Chemical Structure

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生物活性

Carbonic anhydrase inhibitor 9 is a potent carbonic anhydrase (CA) inhibitor with Kis of 56.4 and 56.9 nM for hCA II and IX, respectively. Antiproliferative activity[1].

体外研究
(In Vitro)

Carbonic anhydrase inhibitor 9 (compound 3c) exerts only cytotoxic activity against A549 cell line with IC50=5.90 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

530.39

Formula

C22H20BrN5O4S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Said MF, et al. Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity. J Enzyme Inhib Med Chem. 2022;37(1):701-717.

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