10Z-Hymenialdisine(Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

10Z-Hymenialdisine (Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

10Z-Hymenialdisine ((Z)-Hymenialdisine) 是一种天然的生物活性吡咯生物碱。10Z-Hymenialdisine 是一种泛激酶抑制剂，具有抗癌活性。

10Z-Hymenialdisine(Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

10Z-Hymenialdisine Chemical Structure

CAS No. : 82005-12-7

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生物活性

10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1].

体外研究
(In Vitro)

10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50 value of 6 nM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

324.13

Formula

C11H10BrN5O2
CAS 号

82005-12-7
中文名称

2,5-已炔二醇；已炔二醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ashraf N E Hamed, et al. Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. Z Naturforsch C J Biosci. 2018 Apr 25;73(5-6):199-210.

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