MRT-14

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

MRT-14 

MRT-14 是 Smo 的有效拮抗剂。Smo 是参与 Hedgehog (Hh) 形态发生素信号转导的主要成分。MRT-14 具有研究与异常 Hh 信号传导相关的多种癌症的潜力。

MRT-14

MRT-14 Chemical Structure

CAS No. : 1263131-83-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling[1].

分子量

448.47

Formula

C24H24N4O5

CAS 号

1263131-83-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务