Carbonic anhydrase inhibitor 11

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Carbonic anhydrase inhibitor 11 

Carbonic anhydrase inhibitor 11 (compound VI) 是一种有效的选择性碳酸酐酶抑制剂。Carbonic anhydrase inhibitor 11 对 CA II、IX 和 XII 的 Ki 值分别为 40、39、200 和 900 nM。

Carbonic anhydrase inhibitor 11

Carbonic anhydrase inhibitor 11 Chemical Structure

CAS No. : 2411059-71-5

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生物活性

Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 11 shows Ki values of 40, 39, 200 and 900 nM against CA II, IX, and XII, respectively[1].

分子量

468.47

Formula

C19H15F3N4O3S2
CAS 号

2411059-71-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Abdel-Mohsen HT, et al. Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors. Eur J Med Chem. 2022;228:114004.

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