上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
BLK-IN-2
BLK-IN-2 (compound 25) 是一种有效的，选择性和不可逆的 B-淋巴酪氨酸激酶 (BLK) 抑制剂，IC50 值为 5.9 nM。BLK-IN-2 还可以抑制 BTK (IC50=202.0 nM)。BLK-IN-2 对几种淋巴瘤细胞显示出有效的抗增殖活性。
BLK-IN-2 Chemical Structure
CAS No. : 2694871-86-6
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
BLK-IN-2 (compound 25) is a potent and selective irreversible inhibitor of B-Lymphoid tyrosine kinase (BLK), with an IC50 of 5.9 nM. BLK-IN-2 also inhibits BTK (IC50=202.0 nM). BLK-IN-2 shows potent antiproliferative activities against several lymphoma cells[1]. |
IC50 & Target |
IC50: 5.9 nM (BLK)[1], 202.0 nM (BTK)[1] |
|---|---|
| 分子量 |
683.80 |
| Formula |
C39H41N9O3 |
| CAS 号 |
2694871-86-6 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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