Bis-Pro-5FU

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Bis-Pro-5FU 

Bis-Pro-5FU (Compound 4) 是一种 5-FU 前体,可增强5-氟尿嘧啶 (5-FU) 的口服生物利用度并提高其疗效。5-FU 是一种抗肿瘤抗代谢物,广泛用于结直肠癌和胰腺癌的研究。

Bis-Pro-5FU

Bis-Pro-5FU Chemical Structure

CAS No. : 2155827-07-7

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生物活性

Bis-Pro-5FU (Compound 4) is a 5-FU precursor that confers oral bioavailability and increase the safety profile of 5-Fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antineoplastic antimetabolite that is widely used for the research of colorectal and pancreatic cancer[1].

分子量

206.17

Formula

C10H7FN2O2

CAS 号

2155827-07-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Catherine Adam, et al. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo. J Med Chem. 2022 Jan 13;65(1):552-561.

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