上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Trk-IN-7
Trk-IN-7 (compound I-6) 是一种有效的 Trk 抑制剂，对 TRKA、TRKB 和 TRKC的 IC50 分别为0.25-10 nM。Trk-IN-7 对 EML4-ALK (IC50<15 nm)、alk g1202r、alk c1156y、alk r1275q、alk f1174l、alk l1197m 和 alk g1269a (IC50=5-50 nM) 有抑制作用。
Trk-IN-7 Chemical Structure
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Trk-IN-7 (compound I-6) is a potent TRK inhibitor with IC50s of ranging from 0.25-10 nM for TRKA, TRKB and TRKC, respectively. Trk-IN-7 shows inhibition against EML4-ALK (IC50<15 nm) alk g1202r, c1156y, r1275q, f1174l, l1197m, and g1269a (IC50=5-50 nM)[1]. |
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| IC50 & Target[1] |
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| 分子量 |
368.36 |
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| Formula |
C18H17FN6O2 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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