ATR-IN-6

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ATR-IN-6 

ATR-IN-6 是一种有效的 ATR 抑制剂。ATR 是一类参与基因组稳定性和 DNA 损伤修复的蛋白激酶,是 PIKK 家族的成员。ATR-IN-6 具有研究ATR激酶介导的疾病如增殖性疾病和癌症的潜力 (信息摘自专利 WO2021233376A1,化合物 A22)。

ATR-IN-6

ATR-IN-6 Chemical Structure

CAS No. : 2746446-99-9

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生物活性

ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22)[1].

分子量

513.57

Formula

C28H28FN7O2

CAS 号

2746446-99-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhao, Yanping, et al. 2,4,6-Trisubstituted pyrimidine compounds as atr kinase inhibitors. Patent WO2021233376A1.

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