Chevalone C

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Chevalone C 

Chevalone C 是一种半萜类真菌代谢产物，具有抗疟活性，IC50 值为 25 μg/mL。Chevalone C 对结肠癌 HCT116、肝癌 HepG2 和黑色素瘤 A375 细胞系具有抗增殖活性。

Chevalone C

Chevalone C Chemical Structure

CAS No. : 1318025-77-2

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生物活性

Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2].

体外研究
(In Vitro)

Chevalone C (1, 10, 50, 100, 200 μM; 24 hours) exhibits a significant decrease of cell viability in HepG2, HCT116 and HT29 cell lines (ic50=153 μM, 190 μM, 98 μM)[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

456.61

Formula

C28H40O5
CAS 号

1318025-77-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sasiphimol Sawadsitang, et al. Antimalarial and cytotoxic constituents of Xylaria cf. cubensis PK108. Nat Prod Res. 2015;29(21):2033-6.

    [2]. M Prata-Sena, et al.  Cytotoxic activity of Secondary Metabolites from Marine-derived Fungus Neosartorya siamensis in Human Cancer Cells. Phytother Res. 2016 Nov;30(11):1862-1871.

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