19,20-Epoxycytochalasin C

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

19,20-Epoxycytochalasin C 

19,20-Epoxycytochalasin C 是一种细胞松弛素，是一种来自 Nemania sp 的真菌代谢物。19,20-Epoxycytochalasin C 显示出有效的体外抗疟原虫活性和植物毒性。

19,20-Epoxycytochalasin C

19,20-Epoxycytochalasin C Chemical Structure

CAS No. : 189351-79-9

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生物活性

19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity[1].

IC50 & Target

Microbial Metabolite

 

体外研究
(In Vitro)

19,20-Epoxycytochalasin C shows moderate toxicity to cell line SK-MEL with an IC50 of 8.02 µM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

523.62

Formula

C30H37NO7
CAS 号

189351-79-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mallika Kumarihamy, et al. Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf. Molecules. 2019 Feb 21;24(4):777.

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