19,20-Epoxycytochalasin C

发表于由

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19,20-Epoxycytochalasin C 

19,20-Epoxycytochalasin C 是一种细胞松弛素，是一种来自 Nemania sp 的真菌代谢物。19,20-Epoxycytochalasin C 显示出有效的体外抗疟原虫活性和植物毒性。

19,20-Epoxycytochalasin C

19,20-Epoxycytochalasin C Chemical Structure

CAS No. : 189351-79-9

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生物活性

19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity[1].

IC50 & Target

Microbial Metabolite

 

体外研究
(In Vitro)

19,20-Epoxycytochalasin C shows moderate toxicity to cell line SK-MEL with an IC50 of 8.02 µM[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

523.62

Formula

C30H37NO7
CAS 号

189351-79-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mallika Kumarihamy, et al. Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf. Molecules. 2019 Feb 21;24(4):777.

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