USP5-IN-1 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

USP5-IN-1

USP5-IN-1 (compound 64) 是一种有效的去泛素酶 USP5 抑制剂，与 USP5 ZnF UBD 结合的 K_D 值为 2.8 μM。USP5-IN-1对含有结构相似的 ZnF UBD 结构域的九种蛋白质具有选择性。USP5-IN-1 抑制 USP5 对双泛素底物的催化裂解。

USP5-IN-1 Chemical Structure

规格		是否有货
5 mg		询价
10 mg		询价
50 mg		询价
100 mg		询价

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生物活性	USP5-IN-1 (compound 64), a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a K_D of 2.8 μM. USP5-IN-1 is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate^[1].
分子量	437.90
Formula	C₁₉H₂₀ClN₃O₅S
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Mann MK, et al. Structure-Activity Relationship of USP5 Inhibitors [published correction appears in J Med Chem. 2022 Jan 13;65(1):889]. J Med Chem. 2021;64(20):15017-15036.

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