Teleocidin A1(Synonyms: Lyngbyatoxin A)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Teleocidin A1 (Synonyms: Lyngbyatoxin A)

Teleocidin A1 (Lyngbyatoxin A) 是一种剧毒皮肤刺激物，是蛋白激酶C (PKC) 的有效激活剂。Teleocidin A1 对 HeLa 癌细胞具有抗增殖活性 (IC50=9.2 nM)。

Teleocidin A1(Synonyms: Lyngbyatoxin A)

Teleocidin A1 Chemical Structure

CAS No. : 70497-14-2

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生物活性

Teleocidin A1 (Lyngbyatoxin A), a highly toxic skin irritant, is a potent activator of protein kinase C (PKC). Teleocidin A1 shows antiproliferative activity against HeLa cancer cells (IC50=9.2 nM)[1][2].

分子量

437.62

Formula

C27H39N3O2
CAS 号

70497-14-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Stafford RG, et al. Comparison of the partition coefficient and skin penetration of a marine algal toxin (lyngbyatoxin A). Food Chem Toxicol. 1992;30(9):795-801.

    [2]. Youssef DT, Shaala LA, Mohamed GA, et al. 2,3-seco-2,3-dioxo-lyngbyatoxin A from a Red Sea strain of the marine cyanobacterium Moorea producens. Nat Prod Res. 2015;29(8):703-709.

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