Zaragozic acid B

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Zaragozic acid B 

Zaragozic acid B 是一种真菌代谢产物，是法尼基蛋白转移酶 (FPTase) 和角鲨烯合成酶 (squalene synthases) 的有效抑制剂。Zaragozic acid B 是一种潜在的抗癌药物。

Zaragozic acid B

Zaragozic acid B Chemical Structure

CAS No. : 146389-61-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Zaragozic acid B, a fungal metabolite, is a potent inhibitor of both farnesyl-protein transferase (FPTase) and squalene synthases. Zaragozic acid B is a potential anticancer drug[1].

体外研究
(In Vitro)

Zaragozic acid B is a very potent inhibitor of squalene synthases from all three sources (RSS: rat liver microsome; YSS: Candida albicans; HSS: Hep G2 cells) with the IC50 values range from 0.22 to 0.67 nM[1].
Zaragozic acid B inhibits bovine FPTase (IC50=100 nM), human FPTase (IC50=185 nM)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

730.84

Formula

C39H54O13
CAS 号

146389-61-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Leeyuan Huang, et al. New fungal metabolites as potential antihypercholesterolemics and anticancer agents. Canadian Journal of Botany • December 1995.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务