HDAC6-IN-3 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

HDAC6-IN-3

HDAC6-IN-3 (Compound 14) 是一种抗前列腺癌药物，是一种有效的、具有口服活性的 HDAC6 抑制剂，对 HDAC1/2/3/6/8/10 的 IC₅₀ 范围为 0.02-1.54 μM。HDAC6-IN-3 也是一种有效的 MAO-A (IC₅₀=0.79 μM) 和 LSD1 抑制剂。

HDAC6-IN-3 Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	HDAC6-IN-3 (Compound 14), an antiprostate cancer agent, is a potent, orally active HDAC6 inhibitor with IC₅₀s ranging from 0.02-1.54 μM for HDAC1/2/3/6/8/10. HDAC6-IN-3 is also an effective MAO-A (IC₅₀=0.79 μM) and LSD1 inhibitor^[1].
分子量	345.44
Formula	C₁₉H₂₇N₃O₃
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Ojha R, et al. Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent. J Med Chem. 2021;64(24):17824-17845.

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