MC-Val-Cit-PAB-NH-C2-NH-Boc

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

MC-Val-Cit-PAB-NH-C2-NH-Boc  纯度: ≥95.0%

MC-Val-Cit-PAB-NH-C2-NH-Boc 是一种可被组织蛋白酶 (cathepsin) 降解的 ADC 连接子 (ADC linker)，可用于合成抗体偶联药物 (ADC)。

MC-Val-Cit-PAB-NH-C2-NH-Boc

MC-Val-Cit-PAB-NH-C2-NH-Boc Chemical Structure

CAS No. : 1616727-22-0

规格 价格 是否有货 数量
5 mg ￥3900 In-stock
10 mg ￥6250 In-stock
25 mg ￥12500 In-stock
50 mg   询价  
100 mg   询价  

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生物活性

MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

758.86

Formula

C36H54N8O10
CAS 号

1616727-22-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.

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