eIF4E-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

eIF4E-IN-1 

eIF4E-IN-1 是一种有效的 eIF4E 抑制剂。eIF4E-IN-1 抑制免疫检查点蛋白 PD-1、PD-L1、LAG3、TIM3 和/或 IDO 等免疫抑制成分，以抑制或释放某些疾病 (如癌症和传染病) 的免疫抑制 (信息摘自专利 WO2021003194A1，compound Y)。

eIF4E-IN-1

eIF4E-IN-1 Chemical Structure

CAS No. : 2573979-31-2

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生物活性

eIF4E-IN-1 is a potent inhibitor of eIF4E. eIF4E-IN-1 inhibits immunosuppression components such as immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immune suppression in certain diseases, such as cancer and infectious disease (extracted from patent WO2021003194A1, compound Y)[1].

IC50 & Target

eIF4E[1]
分子量

697.13

Formula

C33H28ClF3N6O4S
CAS 号

2573979-31-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kevin R, et al. Eif4e inhibitors for use as immune checkpoint modulators and related methods. Patent WO2021003194A1.

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