上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
CDK7-IN-6
CDK7-IN-6 是一种有效的选择性细胞周期蛋白依赖性激酶 (CDK7) 抑制剂 (IC50≤100 nM),来自专利 WO2019197549 A1,compound 210。CDK7- IN-6 对 CDK7 的选择性比 CDK1、CDK2 和 CDK5 高 200 倍以上。CDK7-IN-6 可用于癌症研究。
CDK7-IN-6 Chemical Structure
CAS No. : 2378710-04-2
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生物活性 |
CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
CDK7-IN-6 inhibits the viability of HCT116, H460, MV4-11, A2780, and OVCAR cells (IC50≤1 μM)[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
524.06 |
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Formula |
C26H34ClN9O |
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CAS 号 |
2378710-04-2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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