CP-67804

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CP-67804 

CP-67804，喹诺酮类衍生物，是一种拓扑异构酶 II (topoisomerase II) 靶向制剂。CP-67804有效增强真核生物拓扑异构酶 II 介导的DNA切割。CP-67804 具有潜在的抗肿瘤作用。

CP-67804

CP-67804 Chemical Structure

CAS No. : 103978-08-1

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生物活性

CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1].

IC50 & Target[1]

Topoisomerase II

 

体外研究
(In Vitro)

CP-67804 increases topoisomerase II-mediated DNA breakages by enhancing the enzyme’s forward rate of cleavage[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

345.30

Formula

C18H13F2NO4
CAS 号

103978-08-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266(22):14585-14592.

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