Lenalidomide-C5-amido-Boc

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Lenalidomide-C5-amido-Boc  纯度: 95.10%

Lenalidomide-C5-amido-Boc 是一种基于 Lenalidomide 的，可募集 CRBN 蛋白的 Cereblon 配体。Lenalidomide-C5-amido-Boc 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。

Lenalidomide-C5-amido-Boc

Lenalidomide-C5-amido-Boc Chemical Structure

CAS No. : 2138441-25-3

规格 价格 是否有货 数量
100 mg ￥2900 In-stock
500 mg ￥8800 In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

生物活性

Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].

IC50 & Target[1] [1]

Cereblon

 

分子量

429.51

Formula

C23H31N3O5
CAS 号

2138441-25-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献

  • [1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12.

    [2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务