Progesterone-d9(Synonyms: Pregn-4-ene-3,20-dione-d9)

发表于由

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Progesterone-d9 (Synonyms: Pregn-4-ene-3,20-dione-d9)

Progesterone-d9 (Pregn-4-ene-3,20-dione-d9) 是 Progesterone 的氘代物。Progesterone是一种类固醇激素，可调节月经周期，对怀孕很重要。

Progesterone-d9(Synonyms: Pregn-4-ene-3,20-dione-d9)

Progesterone-d9 Chemical Structure

CAS No. : 15775-74-3

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生物活性

Progesterone-d9 (Pregn-4-ene-3,20-dione-d9) is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

323.52

Formula

C21H21D9O2
CAS 号

15775-74-3
中文名称

孕酮 d9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.

    [3]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78.

    [4]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50.

    [5]. Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9.

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