Coenzyme Q10-d9(Synonyms: CoQ10-d9; Ubiquinone-10-d9)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Coenzyme Q10-d9 (Synonyms: CoQ10-d9; Ubiquinone-10-d9)

Coenzyme Q10-d9 (CoQ10-d9) 是 Coenzyme Q10 的氘代物。Coenzyme Q10是电子传递链的重要辅助因子，也是一种有效的抗氧化剂。

Coenzyme Q10-d9(Synonyms: CoQ10-d9; Ubiquinone-10-d9)

Coenzyme Q10-d9 Chemical Structure

CAS No. : 2687960-97-8

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生物活性

Coenzyme Q10-d9 (CoQ10-d9) is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

872.40

Formula

C59H81D9O4
CAS 号

2687960-97-8
中文名称

辅酶Q10 d9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Yang YK, et al. Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clin Chim Acta. 2015 Oct 23;450:83-9.

    [3]. Bhagavan HN, et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006 May;40(5):445-53.

    [4]. Matthews RT, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8892-7.

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