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Idroxioleic acid (Synonyms: (R)-2-Hydroxyoleic acid; (R)-2-OHOA)
Idroxoleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) 是 (Rac)-Idroxoleic acid 的 R 对映异构体，是一种口服活性脂肪酸，可调节膜的脂质组成和结构。Idroxoleic acid 具有抗肿瘤活性。
Idroxioleic acid Chemical Structure
CAS No. : 182370-45-2
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| 生物活性 |
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities[1]. |
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| 体外研究 (In Vitro) |
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA; 400 mg/kg; p.o.; daily; for 21 days) causes a reduction in tumor volume of about 20-25% after 21 days[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 分子量 |
298.46 |
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| Formula |
C18H34O3 |
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| CAS 号 |
182370-45-2 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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