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Artemisinin-d4 (Synonyms: Qinghaosu-d4; NSC 369397-d4)
Artemisinin-d4 (Qinghaosu-d4) 是 Artemisinin 的氘代物。Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，从青蒿 (Artemisia annua L.) 植物的地上部分分离的抗疟疾药物。Artemisinin 以剂量依赖性方式降低 pAKT 来抑制 AKT 信号通路。Artemisinin 可减少癌细胞的增殖，迁移，侵袭，肿瘤发生和转移，同时 Artemisinin 有神经保护作用。
Artemisinin-d4 Chemical Structure
| 规格 | 是否有货 | ||
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Artemisinin-d4 (Qinghaosu-d4) is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2]. |
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| 体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
286.36 |
| Formula |
C15H18D4O5 |
| 中文名称 |
青蒿素 d4 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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