Prednisone-d8(Synonyms: Dehydrocortisone-d8)

发表于由

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Prednisone-d8 (Synonyms: Dehydrocortisone-d8)

Prednisone-d8 (Dehydrocortisone-d8) 是 Prednisone 的氘代物。Prednisone (Adasone)是皮质类固醇试剂，有免疫抑制作用。

Prednisone-d8(Synonyms: Dehydrocortisone-d8)

Prednisone-d8 Chemical Structure

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生物活性

Prednisone-d8 (Dehydrocortisone-d8) is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

366.48

Formula

C21H18D8O5
中文名称

强的松 d8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96.

    [3]. Zhang H, et al. Prednisone adding to usual care treatment for refractory decompensated congestive heart failure. Int Heart J. 2008 Sep;49(5):587-95.

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