Lycopsamine-d7

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Lycopsamine-d7 

(+)-Lycopsamine-d7 是 Lycopsamine 的氘代物。Lycopsamine是一种吡啶类生物碱，可从 Eupatorium maculatum L. 分离得到，具有潜在的抗肿瘤活性。

Lycopsamine-d7

Lycopsamine-d7 Chemical Structure

CAS No. : 2714488-78-3

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生物活性

(+)-Lycopsamine-d7 is the deuterium labeled Lycopsamine. Lycopsamine, a pyrrolizidine alkaloid, is a potential antitumor agent isolated from Eupatorium maculatum L.[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

306.41

Formula

C15H18D7NO5
CAS 号

2714488-78-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. L H Zalkow, et al. Synthesis of Pyrrolizidine Alkaloids Indicine, Intermedine, Lycopsamine, and Analogues and Their N-oxides. Potential Antitumor Agents. J Med Chem. 1985 Jun;28(6):687-94.

    [3]. H Wiedenfeld, et al. Lycopsamine and Cumambrin B From Eupatorium Maculatum. Pharmazie. 2009 Jun;64(6):415-6.

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