Salvigenin-d9(Synonyms: 三裂鼠尾草素 d9)

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Salvigenin-d9 (Synonyms: 三裂鼠尾草素 d9)

Salvigenin-d9 是 Salvigenin 的氘代物。Salvigenin 是一种天然的多酚类化合物，具有神经保护作用。Salvigenin 具有抗肿瘤、细胞毒和免疫调节作用。

Salvigenin-d9(Synonyms: 三裂鼠尾草素 d9)

Salvigenin-d9 Chemical Structure

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生物活性

Salvigenin-d9 is the deuterium labeled Salvigenin. Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

337.37

Formula

C18H7D9O6
中文名称

三裂鼠尾草素 d9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Rafatian G, et al. Increase of autophagy and attenuation of apoptosis by Salvigenin promote survival of SH-SY5Y cells following treatment with H₂O₂. Mol Cell Biochem. 2012 Dec;371(1-2):9-22.

    [3]. Noori S, et al. Antitumor and immunomodulatory effects of salvigenin on tumor bearing mice. Cell Immunol. 2013 Nov-Dec;286(1-2):16-21.

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