Glycerophosphate-d5 disodium pentahydrate(Synonyms: 五水β-甘油磷酸钠 d5 (二钠五水合物))

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Glycerophosphate-d5 disodium pentahydrate (Synonyms: 五水β-甘油磷酸钠 d5 (二钠五水合物))

Glycerophosphate-d5 disodium pentahydrate 是 β-Glycerophosphate disodium salt pentahydrate 的氘代物。β-Glycerophosphate disodium salt pentahydrate 是一种磷酸酶 (phosphatase) 抑制剂。

Glycerophosphate-d5 disodium pentahydrate(Synonyms: 五水β-甘油磷酸钠 d5 (二钠五水合物))

Glycerophosphate-d5 disodium pentahydrate Chemical Structure

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生物活性

Glycerophosphate-d5 disodium pentahydrate is the deuterium labeled β-Glycerophosphate disodium salt pentahydrate. β-Glycerophosphate disodium salt pentahydrate is a phosphatase inhibitor[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

311.14

Formula

C3H12D5Na2O11P
中文名称

五水β-甘油磷酸钠 d5 (二钠五水合物)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Belfield A, et al. Inhibition of the nucleotidase effect of alkaline phosphatase by beta-glycerophosphate. Nature. 1968 Jul 6;219(5149):73-5.

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