Teprasiran(Synonyms: QPI-1002)

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Teprasiran (Synonyms: QPI-1002)

Teprasiran (QPI-1002) 是一种小干扰 RNA，可抑制急性肾损伤中p53 介导的细胞死亡。

Teprasiran(Synonyms: QPI-1002)

Teprasiran Chemical Structure

CAS No. : 1231737-88-4

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生物活性

Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI)[1].

体外研究
(In Vitro)

Teprasiran is a synthetic, chemically stabilized small interfering RNA (siRNA) acting through RNA interference, which temporarily inhibits p53 expression for ≈48 to 72 hours[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 号

1231737-88-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Matthias Thielmann, et al. Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 2021;144:1133-1144.

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