IL-4-inhibitor-1

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IL-4-inhibitor-1 

IL-4-inhibitor-1 (compound 52) 是 IL-4 的抑制剂,其 EC50 值为 1.81 µM。

IL-4-inhibitor-1

IL-4-inhibitor-1 Chemical Structure

CAS No. : 1332184-63-0

规格 是否有货
5 mg 询价
50 mg 询价

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生物活性

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1].

IC50 & Target

EC50: 1.81 µM (IL-4)[1].

体外研究
(In Vitro)

IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context[1].
IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC50 value of 3.1 µM, but did not affect the levels of STAT-6[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

321.31

Formula

C18H12FN3O2

CAS 号

1332184-63-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Sean P Quinnell, et al. A Small-Molecule Inhibitor to the Cytokine Interleukin-4. ACS Chem Biol. 2020 Oct 16;15(10):2649-2654.

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